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one commonly quoted CAS number, 1005-39-6, belongs to 2-methylsulfanylpyrimidine-4,6-diamine, an unrelated compound

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While this methylation reaction was historically considered a relatively minor metabolic pathway for nicotinamide clearance, research over the past decade has revealed that NNMT plays a surprisingly important and previously underappreciated role in cellular energy metabolism, NAD+ homeostasis, adipocyte biology, and whole-body metabolic regulation