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111,112 Mn II plays many diverse roles in biology, 113 including that of Lewis acid in transformations that do not require a change in oxidation state, e.g., in phosphatases, arginase and a number of metabolic enzymes, but also in other contexts where Mn III and higher oxidation states are reached, including Mn-superoxide dismutase, some ribonucleotide reductases, and the oxygen evolving complex in plants
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Although it is not necessary as a regular part of their daily diets, it poses many benefits when used as an emergency or healing supplement